Journal: Biomedicines

Article Title: Sulforaphane’s Role in Osteosarcoma Treatment: A Systematic Review and Meta-Analysis of Preclinical Studies

doi: 10.3390/biomedicines13051048

Figure Lengend Snippet: Forest plots showing the effect of 20 μΜ SFN on the viability of ( a ) MG-63 and ( b ) U-2 OS cells. Data from the included studies were categorized into subgroups based on the duration of the 20 μM SFN treatment. The green squares represent the estimated mean difference for each individual study and the black diamond represents the pooled mean difference and the associated 95% CI. The studies included in these forest plots are: Ferreira de Oliveira et al. (2014b) , Kim et al. (2011) , Jeong et al. (2017) , Li et al. (2016) .

Article Snippet: Cell viability , Kim et al., 2011 [ ]; Ferreira de Oliveira et al., 2014b [ ]; Li et al., 2016 [ ] , MG-63 (human) , 5 μΜ , 24 48 72 , −3.13 (−18.02, 11.75) −38.93 (−78.30, 0.45) −23.89 (−31.41, −16.37) , −26.05 (−53.30, 1.19) , Mean difference, IV, Random effects, 95% CI , Chi 2 = 130.38, df = 3, p < 0.00001, I 2 = 98% , Z = 1.87, p = 0.06.

Techniques:

Journal: Biomedicines

Article Title: Sulforaphane’s Role in Osteosarcoma Treatment: A Systematic Review and Meta-Analysis of Preclinical Studies

doi: 10.3390/biomedicines13051048

Figure Lengend Snippet: Forest plots showing the effect of 20 μΜ SFN on the distribution of MG-63 cells in ( a ) G0/G1, ( b ) S, and ( c ) G2/M phases of the cell cycle. Data from the included studies were categorized into subgroups based on the duration of the 20 μM SFN treatment. The green squares represent the estimated mean difference for each individual study and the black diamond represents the pooled mean difference and the associated 95% CI. The studies included in these forest plots are: Ferreira de Oliveira et al. (2014b) , Matsui et al. (2007) , Kim et al. (2011) .

Article Snippet: Cell viability , Kim et al., 2011 [ ]; Ferreira de Oliveira et al., 2014b [ ]; Li et al., 2016 [ ] , MG-63 (human) , 5 μΜ , 24 48 72 , −3.13 (−18.02, 11.75) −38.93 (−78.30, 0.45) −23.89 (−31.41, −16.37) , −26.05 (−53.30, 1.19) , Mean difference, IV, Random effects, 95% CI , Chi 2 = 130.38, df = 3, p < 0.00001, I 2 = 98% , Z = 1.87, p = 0.06.

Techniques:

Journal: Biomedicines

Article Title: Sulforaphane’s Role in Osteosarcoma Treatment: A Systematic Review and Meta-Analysis of Preclinical Studies

doi: 10.3390/biomedicines13051048

Figure Lengend Snippet: Forest plots showing the effect of 20 and 15 μΜ SFN on the percentage of apoptotic MG-63 cells. Data from the included studies were categorized into subgroups based on the duration of the SFN treatment. The green squares represent the estimated std. mean difference for each individual study and the black diamond represents the pooled std. mean difference and the associated 95% CI. The studies included in this forest plot are: Ferreira de Oliveira et al. (2014b) , Li et al. (2016) .

Article Snippet: Cell viability , Kim et al., 2011 [ ]; Ferreira de Oliveira et al., 2014b [ ]; Li et al., 2016 [ ] , MG-63 (human) , 5 μΜ , 24 48 72 , −3.13 (−18.02, 11.75) −38.93 (−78.30, 0.45) −23.89 (−31.41, −16.37) , −26.05 (−53.30, 1.19) , Mean difference, IV, Random effects, 95% CI , Chi 2 = 130.38, df = 3, p < 0.00001, I 2 = 98% , Z = 1.87, p = 0.06.

Techniques: